Identification of the Risk Factors of the Thyroid Cancer in Males, Lahore

Abstract

Thyroid Cancer (TC) has become a common disease in the developing countries. A number of prognostic factors of thyroid cancer have been identified, such as age, gender, iodine deficiency, radiation exposure, food etc. The aim of this study is to explore the different risk factors of the occurrence of thyroid cancer in Pakistan. This study consisted of 88 males, including 33 cases and 55 controls. These individuals were interviewed from the INMOL Hospital and the Sheikh Zayed Hospital, Lahore and all the necessary information was collected. All the possible risk factors were observed descriptively and inferentially. For the Bivariate Analysis, the Chi-square, Phi/v statistics and Kandall’s tau-B are used. For the purpose of Multivariate Analysis, Odds Ratio and 95% confidence interval of these factors were computed by using Logistic Regression model by using the SPSS. In Bivariate Analysis, five factors were found to be positively significant and one was found negatively significant. The Multivariate results showed that the Odds Ratio and 95 % confidence interval (C.I.) for oxidative stress were 10.081 and (2.681-37.902), for fast food they were 6.011 and (1.564- 23.101)and for vegetables they were 8.896 and (0.830-95.340), respectively. It was concluded that oxidative stress has 10 time higher risk of thyroid cancer with the Odds Ratio10.081 and C.I. (2.681-37.902). Moreover, fast food and cruciferous vegetables also increased the risk factor of thyroid cancer.